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NFL Reports: Austin Ekeler to work out for Panthers NFL Panthers RB Jonathon Brooks needs surgery, out at least six weeks NFL Michael Penix: Being healthy was my target, I feel I’m where I want to be NFL Derrick Henry says Ravens weren’t good enough, but not complaining about lack of carries NFL Alleged victim of Daejon Love says she reported him to 49ers in December 2025 NFL Predicting full 14-team NFL playoff bracket entering Week 3, including history-making Super Bowl NFL Super Bowl stock report for Week 3: Bengals are total package, Chargers’ season over before it started NFL Prisco’s Week 3 NFL picks: Browns upset Panthers, Giants rally behind Jameis Winston NFL Resetting expectations for these six NFL teams with injured quarterbacks: Giants eyeing draft again NFL Week 3 NFL odds, picks, predictions: Computer model backs Lions and 49ers NFL Real or not? We rated the sustainability of 32 NFL surprise trends and stats through Week 2 NFL Bucs will regret Mayfield’s contract? Chargers are a bottom-10 team? Solak on Week 2 NFL Sources: Giants QB Dart out for extended period, possibly rest of season NFL Sources: Panthers RB Brooks set for surgery, out at least 6 weeks NFL Reports: Austin Ekeler to work out for Panthers NFL Panthers RB Jonathon Brooks needs surgery, out at least six weeks NFL Michael Penix: Being healthy was my target, I feel I’m where I want to be NFL Derrick Henry says Ravens weren’t good enough, but not complaining about lack of carries NFL Alleged victim of Daejon Love says she reported him to 49ers in December 2025 NFL Predicting full 14-team NFL playoff bracket entering Week 3, including history-making Super Bowl NFL Super Bowl stock report for Week 3: Bengals are total package, Chargers’ season over before it started NFL Prisco’s Week 3 NFL picks: Browns upset Panthers, Giants rally behind Jameis Winston NFL Resetting expectations for these six NFL teams with injured quarterbacks: Giants eyeing draft again NFL Week 3 NFL odds, picks, predictions: Computer model backs Lions and 49ers NFL Real or not? We rated the sustainability of 32 NFL surprise trends and stats through Week 2 NFL Bucs will regret Mayfield’s contract? Chargers are a bottom-10 team? Solak on Week 2 NFL Sources: Giants QB Dart out for extended period, possibly rest of season NFL Sources: Panthers RB Brooks set for surgery, out at least 6 weeks

🏈 NFL Sep 23, 2026 · 1 min read

Week 3 NFL odds, picks, predictions: Computer model backs Lions and 49ers

SportsLine’s advanced model has simulated every game in the Week 3 NFL schedule 10,000 times and locked in its NFL best bets today

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